HAMAP rule MF_00548
General rule information
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Accession | MF_00548 |
Dates | 21-MAR-2002 (Created)
9-MAR-2023 (Last updated, Version 28) |
Name | ZupT |
Scope(s) |
Bacteria |
Template(s) | P0A8H3 (ZUPT_ECOLI); P67470 (ZUPT_SALTY); [ Recover all ] |
Triggered by |
HAMAP; MF_00548 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | ZUPT |
Protein name | RecName: Full=Zinc transporter ZupT; |
Gene name | Name=zupT; |
Comments
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FUNCTION | Mediates zinc uptake. May also transport other divalent cations. |
CATALYTIC ACTIVITY | Reaction=Zn(2+)(in) = Zn(2+)(out); Xref=Rhea:RHEA:29351, ChEBI:CHEBI:29105; |
case not defined <Property:Membrane> or <Property:Membrane=1> | |
SUBCELLULAR LOCATION | Cell membrane; Multi-pass membrane protein. |
else case <Property:Membrane=2> | |
SUBCELLULAR LOCATION | Cell inner membrane; Multi-pass membrane protein. |
end case | |
SIMILARITY | Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily. |
Keywords
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Cell membrane | |
case defined <Property:Membrane> and <Property:Membrane=2> | |
Cell inner membrane | |
end case | |
Ion transport | |
Membrane | |
Transmembrane | |
Transmembrane helix | |
Transport | |
Zinc | |
Zinc transport |
Gene Ontology
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GO:0005385; Molecular function:zinc ion transmembrane transporter activity |
GO:0071577; Biological process:zinc ion transmembrane transport |
GO:0005886; Cellular component:plasma membrane |
Cross-references
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Pfam | PF02535; Zip; 1; |
General | Transmembrane; -; 7-8; |
Features
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From: ZUPT_ECOLI (P0A8H3) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
BINDING | 120 | 120 | /ligand="Fe(2+)" /ligand_id="ChEBI:CHEBI:29033" /note="M2 metal binding site" |
N | ||||||||
BINDING | 123 | 123 | /ligand="Fe(2+)" /ligand_id="ChEBI:CHEBI:29033" /note="M2 metal binding site" |
E | ||||||||
BINDING | 123 | 123 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /note="M1 metal binding site" |
E | ||||||||
BINDING | 148 | 148 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /note="M1 metal binding site" |
H | ||||||||
BINDING | 149 | 149 | /ligand="Fe(2+)" /ligand_id="ChEBI:CHEBI:29033" /note="M2 metal binding site" |
N | ||||||||
BINDING | 152 | 152 | /ligand="Fe(2+)" /ligand_id="ChEBI:CHEBI:29033" /note="M2 metal binding site" |
E | ||||||||
BINDING | 152 | 152 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /note="M1 metal binding site" |
E | ||||||||
BINDING | 181 | 181 | /ligand="Fe(2+)" /ligand_id="ChEBI:CHEBI:29033" /note="M2 metal binding site" |
E |
Additional information
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Size range | 257-291 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |