HAMAP

Accession	MF_00550
Dates	26-APR-2002 (Created) 10-OCT-2011 (Last updated, Version 27)

Data class

Protein

Predictors

HAMAP; MF_00550; [distribution of match scores in UniProtKB];[seed alignment for MF_00550]

Names

Aminopeptidase_M20

Identifier

PEPT

Protein name

RecName: Full=Peptidase T; EC=3.4.11.4; AltName: Full=Aminotripeptidase; Short=Tripeptidase; AltName: Full=Tripeptide aminopeptidase;

Gene name

pepT

FUNCTION: Cleaves the N-terminal amino acid of tripeptides (By similarity).

CATALYTIC ACTIVITY: Release of the N-terminal residue from a tripeptide.

COFACTOR: Binds 2 zinc ions per subunit (By similarity).

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the peptidase M20B family.

PROSITE	PS00758; ARGE_DAPE_CPG2_1; 1; PS00759; ARGE_DAPE_CPG2_2; 1;
Pfam	PF07687; M20_dimer; 1; PF01546; Peptidase_M20; 1;
TIGRFAMs	TIGR01882; Peptidase-T; 1;

Cytoplasm, Hydrolase, Protease, Aminopeptidase, Metalloprotease, Metal-binding, Zinc.

GO:0045148; Molecular function: tripeptide aminopeptidase activity.
GO:0008270; Molecular function: zinc ion binding.
GO:0006508; Biological process: proteolysis.
GO:0005737; Cellular component: cytoplasm.

From: PEPT_SALTY (P26311)
Key		From		To		Description		Condition		FTGroup
ACT_SITE		80		80		By similarity		D
ACT_SITE		173		173		Proton acceptor (By similarity)		E
METAL		78		78		Zinc 1 (By similarity)		H
METAL		140		140		Zinc 1 (By similarity)		D
METAL		140		140		Zinc 2 (By similarity)		D
METAL		174		174		Zinc 2 (By similarity)		E
METAL		196		196		Zinc 1 (By similarity)		D
METAL		379		379		Zinc 2 (By similarity)		H

Size range:	406-413 amino acids
Related UniRules:	None
Template:	P26311 (PEPT_SALTY); P55179 (PEPT_BACSU); P29745 (PEPT_ECOLI); P0C2T7 (PEPT_LACLC); Q9L4G1 (PEPT_LACHE); P81207 (PEPT_FUSNP): [Recover all]
Scope:	Bacteria
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None