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HAMAP rule MF_00555

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General rule information [?]

Accession MF_00555
Dates 16-MAY-2002 (Created)
1-JUN-2023 (Last updated, Version 29)
Name AsnA
Scope(s) Bacteria
Template(s) P00963 (ASNA_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_00555 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier ASNA
Protein name RecName: Full=Aspartate--ammonia ligase;
                 EC=6.3.1.1;
AltName: Full=Asparagine synthetase A;
Gene name Name=asnA;

Comments [?]

CATALYTIC ACTIVITY Reaction=ATP + L-aspartate + NH4(+) = AMP + diphosphate + H(+) + L- asparagine; Xref=Rhea:RHEA:11372, ChEBI:CHEBI:15378, ChEBI:CHEBI:28938, ChEBI:CHEBI:29991, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:58048, ChEBI:CHEBI:456215; EC=6.3.1.1;
PATHWAYAmino-acid biosynthesis; L-asparagine biosynthesis; L- asparagine from L-aspartate (ammonia route): step 1/1.
SUBCELLULAR LOCATIONCytoplasm.
SIMILARITYBelongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.

Keywords [?]


Gene Ontology [?]

GO:0004071; Molecular function:aspartate-ammonia ligase activity
GO:0005524; Molecular function:ATP binding
GO:0006529; Biological process:asparagine biosynthetic process
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF03590; AsnA; 1;
NCBIfam TIGR00669; AsnA; 1;
PROSITE PS50862; AA_TRNA_LIGASE_II; 1;

Features [?]


Additional information [?]

Size range 322-345 amino acids
Related rules None
Fusion Nter: None Cter: None



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