HAMAP

Accession	MF_00561
Dates	28-MAY-2002 (Created) 25-NOV-2009 (Last updated, Version 16)

Data class

Protein

Predictors

HAMAP; MF_00561; [distribution of match scores in UniProtKB];[seed alignment for MF_00561]

Names

ADP_PFKinase

Identifier

K6PF

Protein name

RecName: Full=ADP-specific phosphofructokinase; EC=2.7.1.146; AltName: Full=ADP-dependent phosphofructokinase; Short=ADP-Pfk;

Gene name

pfkC

FUNCTION: Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor (By similarity).

CATALYTIC ACTIVITY: ADP + D-fructose 6-phosphate = AMP + D-fructose 1,6-bisphosphate.

COFACTOR: Binds 1 magnesium ion per subunit (By similarity).

PATHWAY: Carbohydrate degradation; glycolysis.

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the carbohydrate kinase pfkC family.

SIMILARITY: Contains 1 ADPK (ADP-dependent kinase) domain.

Pfam	PF04587; ADP_PFK_GK; 1;
PROSITE	PS51255; ADPK; 1; trigger=PRU00584;

Cytoplasm, Transferase, Kinase, Glycolysis, Magnesium, Metal-binding.

GO:0016773; Molecular function: phosphotransferase activity, alcohol group as acceptor.
GO:0006096; Biological process: glycolysis.
GO:0005737; Cellular component: cytoplasm.

From: K6PF_METJA (Q58999)
Key		From		To		Description		Condition		FTGroup
ACT_SITE		442		442		Proton acceptor (By similarity)		D
METAL		272		272		Magnesium (By similarity)		E
METAL		302		302		Magnesium (By similarity)		E
METAL		442		442		Magnesium (By similarity)		D

Size range:	450-491 amino acids
Related UniRules:	MF_00809 (GLKA)
Template:	Q58999 (K6PF_METJA); Q9V2Z7 (K6PF_PYRFU): [Recover all]
Scope:	Archaea
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None