HAMAP rule MF_00561
General rule information
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| Accession | MF_00561 |
| Dates | 28-MAY-2002 (Created)
1-JUN-2023 (Last updated, Version 29) |
| Name | ADP_PFKinase |
| Scope(s) |
Archaea |
| Template(s) | Q58999 (K6PF_METJA); Q9V2Z7 (K6PF_PYRFU); [ Recover all ] |
| Triggered by |
HAMAP; MF_00561 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | K6PF |
| Protein name | RecName: Full=ADP-specific phosphofructokinase; EC=2.7.1.146; AltName: Full=ADP-dependent phosphofructokinase; Short=ADP-Pfk; |
| Gene name | Name=pfkC; |
Comments
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| FUNCTION | Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor. |
| CATALYTIC ACTIVITY | Reaction=ADP + beta-D-fructose 6-phosphate = AMP + beta-D-fructose 1,6- bisphosphate + H(+); Xref=Rhea:RHEA:20105, ChEBI:CHEBI:15378, ChEBI:CHEBI:32966, ChEBI:CHEBI:57634, ChEBI:CHEBI:456215, ChEBI:CHEBI:456216; EC=2.7.1.146; |
| COFACTOR | Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Note=Binds 1 Mg(2+) ion per subunit.; |
| PATHWAY | Carbohydrate degradation; glycolysis. |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the carbohydrate kinase PfkC family. |
Keywords
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Gene Ontology
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| GO:0016773; Molecular function:phosphotransferase activity, alcohol group as acceptor |
| GO:0006096; Biological process:glycolytic process |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
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Features
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| From: K6PF_METJA (Q58999) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| ACT_SITE | 442 | 442 | /note="Proton acceptor" | D | ||||||||
| BINDING | 272 | 272 | /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420" |
E | ||||||||
| BINDING | 302 | 302 | /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420" |
E | ||||||||
| BINDING | 442 | 442 | /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420" |
D | ||||||||
Additional information
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| Size range | 440-505 amino acids |
| Related rules |
MF_00809 |
| Fusion | Nter: None Cter: None |