HAMAP

Accession	MF_00586
Dates	21-OCT-2002 (Created) 10-OCT-2011 (Last updated, Version 17)

Data class

Protein

Predictors

HAMAP; MF_00586; [distribution of match scores in UniProtKB];[seed alignment for MF_00586]

Names

GatD

Identifier

GATD

Protein name

RecName: Full=Glutamyl-tRNA(Gln) amidotransferase subunit D; Short=Glu-ADT subunit D; EC=6.3.5.-;

Gene name

gatD

FUNCTION: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The gatDE system is specific for glutamate and does not act on aspartate (By similarity).

CATALYTIC ACTIVITY: ATP + L-glutamyl-tRNA(Gln) + L-glutamine = ADP + phosphate + L-glutaminyl-tRNA(Gln) + L-glutamate.

SUBUNIT: Heterodimer of gatD and gatE (By similarity).

SIMILARITY: Belongs to the asparaginase 1 family. GatD subfamily.

Pfam	PF00710; Asparaginase; 1;
PRINTS	PR00139; ASNGLNASE; 1;
TIGRFAMs	TIGR00519; AsnASE_I; 1;
PROSITE	PS00144; ASN_GLN_ASE_1; 1; PS00917; ASN_GLN_ASE_2; 1;

ATP-binding, Ligase, Nucleotide-binding, Protein biosynthesis.

GO:0050567; Molecular function: glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity.
GO:0006412; Biological process: translation.

From: GATD_METTH (O26802)
Key		From		To		Description		Condition		FTGroup
ACT_SITE		101		101		By similarity		T
ACT_SITE		177		177		By similarity		T
ACT_SITE		178		178		By similarity		D
ACT_SITE		254		254		By similarity		K

Size range:	406-458 amino acids
Related UniRules:	None
Template:	O26802 (GATD_METTH)
Scope:	Archaea
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None