HAMAP

Accession	MF_00588
Dates	22-OCT-2002 (Created) 11-AUG-2011 (Last updated, Version 17)

Data class

Protein

Predictors

HAMAP; MF_00588; [distribution of match scores in UniProtKB];[seed alignment for MF_00588]

Names

GatE

Identifier

GATE

Protein name

RecName: Full=Glutamyl-tRNA(Gln) amidotransferase subunit E; Short=Glu-ADT subunit E; EC=6.3.5.-;

Gene name

gatE

FUNCTION: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate (By similarity).

CATALYTIC ACTIVITY: ATP + L-glutamyl-tRNA(Gln) + L-glutamine = ADP + phosphate + L-glutaminyl-tRNA(Gln) + L-glutamate.

SUBUNIT: Heterodimer of GatD and GatE (By similarity).

SIMILARITY: Belongs to the GatB/GatE family. GatE subfamily.

Pfam	PF02938; GAD; 1; PF02934; GatB_N; 1; PF02637; GatB_Yqey; 1;
TIGRFAMs	TIGR00134; GatE_arch; 1;
PROSITE	PS01234; GATB; 1;

ATP-binding, Ligase, Nucleotide-binding, Protein biosynthesis.

GO:0050567; Molecular function: glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity.
GO:0006412; Biological process: translation.

Size range:	598-642 amino acids
Related UniRules:	MF_00121 (GATB)
Template:	O26803 (GATE_METTH)
Scope:	Archaea
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None