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HAMAP rule MF_00591

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General rule information [?]

Accession MF_00591
Dates 5-MAR-2003 (Created)
1-JUN-2023 (Last updated, Version 20)
Name Exosome_Rrp41
Scope(s) Archaea
Template(s) Q9UXC2 (RRP41_SACS2); O29757 (RRP41_ARCFU); O26779 (RRP41_METTH); Q9V119 (RRP41_PYRAB); [ Recover all ]
Triggered by HAMAP; MF_00591 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier RRP41
Protein name RecName: Full=Exosome complex component Rrp41;
                 EC=3.1.13.-;
Gene name Name=rrp41;

Comments [?]

FUNCTIONCatalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails.
SUBUNITComponent of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
SUBCELLULAR LOCATIONCytoplasm.
SIMILARITYBelongs to the RNase PH family. Rrp41 subfamily.

Keywords [?]


Gene Ontology [?]

GO:0000175; Molecular function:3'-5'-RNA exonuclease activity
GO:0006401; Biological process:RNA catabolic process
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF01138; RNase_PH; 1;
Pfam PF03725; RNase_PH_C; 1;
NCBIfam TIGR02065; ECX1; 1;

Features [?]


Additional information [?]

Size range 230-501 amino acids
Related rules None
Fusion Nter: None Cter: <Unknown>



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