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HAMAP annotation rule: MF_00592
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General rule information

Accession MF_00592
Dates 1-NOV-2002 (Created)
24-MAR-2011 (Last updated, Version 29)
Data class Protein
Predictors HAMAP; MF_00592; [distribution of match scores in UniProtKB];[seed alignment for MF_00592]
Names DeoC_type2


Propagated annotation

Identifier, protein and gene names
Identifier DEOC
Protein name
RecName: Full=Deoxyribose-phosphate aldolase;
Short=DERA;
EC=4.1.2.4;
AltName: Full=2-deoxy-D-ribose 5-phosphate aldolase;
AltName: Full=Phosphodeoxyriboaldolase;
Short=Deoxyriboaldolase;
Gene name deoC
Comments
FUNCTION: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate (By similarity).
CATALYTIC ACTIVITY: 2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde.
PATHWAY: Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2.
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
SIMILARITY: Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
Cross-references
Pfam PF01791; DeoC; 1;
Keywords

case (<OC:Escherichia> or <OC:Shigella>) and <FT:3>
Acetylation.
end case

Cytoplasm, Lyase, Schiff base.
Gene Ontology
GO:0004139; Molecular function: deoxyribose-phosphate aldolase activity.
GO:0016052; Biological process: carbohydrate catabolic process.
GO:0005737; Cellular component: cytoplasm.
Features
From: DEOC_ECOLI (P0A6L0)
Key     From     To       Description   Condition   FTGroup
ACT_SITE     167     167       Schiff-base intermediate with acetaldehyde (By similarity)   K  
ACT_SITE     201     201       By similarity   K  
case <OC:Escherichia> or <OC:Shigella>
Key     From     To       Description   Condition   FTGroup
MOD_RES     167     167       N6-acetyllysine (By similarity)   K  
end case



Additional information

Size range: 255-265 amino acids
Related UniRules: MF_00114 (DEOC)
Template: P0A6L0 (DEOC_ECOLI)
Scope: Bacteria
Fusion: Nter: None; Cter: None
Duplicate: None
Plasmid encoded: None

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UniProtKB rule member sequences