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HAMAP annotation rule: MF_00600
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General rule information

Accession MF_00600
Dates 15-NOV-2002 (Created)
22-OCT-2010 (Last updated, Version 52)
Data class Protein
Predictors HAMAP; MF_00600; [distribution of match scores in UniProtKB];[seed alignment for MF_00600]
Names CH60


Propagated annotation

Identifier, protein and gene names
Identifier CH60

case not <OG:Chloroplast>
Protein name
RecName: Full=60 kDa chaperonin;
AltName: Full=Protein Cpn60;
AltName: Full=GroEL protein;

else case <OG:Chloroplast>
Protein name
RecName: Full=60 kDa chaperonin, chloroplastic;
AltName: Full=Protein Cpn60;
AltName: Full=GroEL protein;
end case

Gene name groL, groEL
Comments
FUNCTION: Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity).
SUBUNIT: Oligomer of 14 subunits composed of two stacked rings of 7 subunits (By similarity).

case not <OG:Chloroplast>
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
end case


case <OG:Chloroplast>
SUBCELLULAR LOCATION: Plastid, chloroplast.
end case

SIMILARITY: Belongs to the chaperonin (HSP60) family.
Cross-references
Pfam PF00118; Cpn60_TCP1; 1;
PRINTS PR00298; CHAPERONIN60; 1;
TIGRFAMs TIGR02348; GroEL; 1;
PROSITE PS00296; CHAPERONINS_CPN60; 1;
Keywords

case <FT:1>
Acetylation.
end case

ATP-binding, Chaperone.

case not <OG:Chloroplast>
Cytoplasm.
end case

Nucleotide-binding.
Gene Ontology
GO:0005524; Molecular function: ATP binding.
GO:0051082; Molecular function: unfolded protein binding.
GO:0042026; Biological process: protein refolding.

case not <OG:Chloroplast>
GO:0005737; Cellular component: cytoplasm.
end case


case <OG:Chloroplast>
GO:0009507; Cellular component: chloroplast.
end case

Features

case <OC:Escherichia> or <OC:Shigella>
From: CH60_ECOLI (P0A6F5)
Key     From     To       Description   Condition   FTGroup
MOD_RES     117     117       N6-acetyllysine (By similarity)   K  
end case



Additional information

Size range: 518-587 amino acids
Related UniRules: None
Template: P0A6F5 (CH60_ECOLI); P61491 (CH60_THETH); P31293 (CH60_CHRVI); Q60024 (CH60_THEBR): [Recover all]
Scope: Bacteria
Archaea; Methanococcales
Archaea; Methanomicrobiales
Archaea; Methanosarcinaceae
Archaea; Methanospirillaceae
Plastid
Fusion: Nter: None; Cter: None
Duplicate: in ANADE, NOSS1, ANAVT, BRAJA, BURCA, BURP1, BURPS, BURS3, BURTA, BURXL, CHLCV, CHLPN, CHRVO, CORDI, COREF, CORJK, CORGL, FRASC, GLOVI, MESSB, METCA, MOOTA, MYCBO, MYCLE, MYCPA, MYCTU, MYXXD, NITHX, NITWN, NOCFA, PARUW, PROAC, PROM9, PROMA, PROMM, PROMP, PROMT, RHIEC, RHIL3, RHILO, RHIME, RHOBA, RHOFD, RHOP2, RHOPA, RHOPB, RHORT, RHOS4, RHOSR, ROSDO, SALRD, SPHAL, STRAW, STRCO, SYNAS, THEEB, SYNJA, SYNJB, SYNP6, SYNPX, SYNS9, SYNSC, SYNY3, THEFY, VIBCH, VIBPA, VIBVU, VIBVY
Plasmid encoded: in ACAM1, ANAVT, ECOK1, PARDP, RHIEC, RHILO, RHIME, RHISN, SINMW

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UniProtKB rule member sequences