To improve security and privacy, we are moving our web pages and services from HTTP to HTTPS.
To give users of web services time to transition to HTTPS, we will support separate HTTP and HTTPS services until the end of 2017.
From January 2018 most HTTP traffic will be automatically redirected to HTTPS. [more...]
View this page in https
Annotation rule MF_00605
Send feedback

General rule information [?]

Accession MF_00605
Dates 29-NOV-2002 (Created)
26-SEP-2014 (Last updated, Version 22)
Name TrmD
Scope Bacteria
Template P0A873 (TRMD_ECOLI)

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=tRNA (guanine-N(1)-)-methyltransferase;
AltName: Full=M1G-methyltransferase;
AltName: Full=tRNA [GM37] methyltransferase;
Gene name

Comments [?]

Function Specifically methylates guanosine-37 in various tRNAs.
Catalytic activity S-adenosyl-L-methionine + guanine(37) in tRNA = S-adenosyl-L-homocysteine + N(1)-methylguanine(37) in tRNA.
Subunit Homodimer.
Subcellular location Cytoplasm.
Similarity Belongs to the RNA methyltransferase TrmD family.

Keywords [?]

Gene Ontology [?]

GO:0009019; Molecular function: tRNA (guanine-N1-)-methyltransferase activity.
GO:0006400; Biological process: tRNA modification.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF01746; tRNA_m1G_MT; 1;
TIGRFAMs TIGR00088; TrmD; 1;

Features [?]

From: TRMD_ECOLI (P0A873)
Key     From     To       Description   Tag   Condition   FTGroup
REGION     133     138       S-adenosyl-L-methionine binding     [ILVM]-G-[DN]-[YF]-[IV]-[ILVM]  
BINDING     113     113       S-adenosyl-L-methionine; via amide nitrogen     G  

Additional information [?]

Size range 222-361 amino acids
Related rules None
Fusion Nter: None; Cter: <Unknown>