HAMAP rule MF_00618

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_00618
Accession	MF_00618
Dates	28-FEB-2005 (Created) 02-FEB-2026 (Last updated, Version )
Name	Ferredoxin_bilin_red
Scope(s)	Bacteria Cyanobacteriota
Template(s)	Q93TN0; Q93TM9; Q55891; [ Recover all ]
Triggered by	HAMAP; MF_00618 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	PCYA
Protein name	RecName: Full=Phycocyanobilin:ferredoxin oxidoreductase; EC=1.3.7.5; AltName: Full=Ferredoxin-dependent bilin reductase; Short=FDBR;
Gene name	Name=pcyA;

Comments [?]

FUNCTION	Catalyzes the four-electron reduction of biliverdin IX-alpha (2-electron reduction at both the A and D rings); the reaction proceeds via an isolatable 2-electron intermediate, 18(1),18(2)- dihydrobiliverdin.
CATALYTIC ACTIVITY	Reaction=(2R,3Z)-phycocyanobilin + 4 oxidized [2Fe-2S]-[ferredoxin] = biliverdin IXalpha + 4 reduced [2Fe-2S]-[ferredoxin] + 4 H(+); Xref=Rhea:RHEA:15309, Rhea:RHEA-COMP:10000, Rhea:RHEA-COMP:10001, ChEBI:CHEBI:15378, ChEBI:CHEBI:33737, ChEBI:CHEBI:33738, ChEBI:CHEBI:57437, ChEBI:CHEBI:57991; EC=1.3.7.5;
SUBUNIT	Monomer.
SIMILARITY	Belongs to the HY2 family.

Keywords [?]

Gene Ontology [?]

GO:0050620; Molecular function:phycocyanobilin:ferredoxin oxidoreductase activity

Cross-references [?]

Pfam	PF05996; Fe_bilin_red; 1;

Features [?]

From: PCYA_SYNY3 (Q55891)

Key

From

Description

Tag

Condition

FTGroup

ACT_SITE

/note="Proton donor"

ACT_SITE

/note="Proton donor"

ACT_SITE

105

/note="Proton donor"

BINDING