Due to maintenance work, this service will not be available Thursday August 21st between 7am and 8am CEST.
Annotation rule MF_00624
Send feedback

General rule information [?]

Accession MF_00624
Dates 11-MAR-2003 (Created)
20-MAR-2014 (Last updated, Version 21)
Name GlgC
Scope Bacteria

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
GLGC
Protein name
RecName: Full=Glucose-1-phosphate adenylyltransferase;
EC=2.7.7.27;
AltName: Full=ADP-glucose pyrophosphorylase;
Short=ADPGlc PPase;
AltName: Full=ADP-glucose synthase;
Gene name
glgC

Comments [?]

Function Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity).
Catalytic activity ATP + alpha-D-glucose 1-phosphate = diphosphate + ADP-glucose.
Pathway Glycan biosynthesis; glycogen biosynthesis.
Similarity Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

Keywords [?]


Gene Ontology [?]

GO:0008878; Molecular function: glucose-1-phosphate adenylyltransferase activity.
GO:0005978; Biological process: glycogen biosynthetic process.

Cross-references [?]

Pfam PF00483; NTP_transferase; 1;
PF00132; Hexapep; 0-4;
TIGRFAMs TIGR02091; GlgC; 1;
PROSITE PS00808; ADP_GLC_PYROPHOSPH_1; 1;
PS00809; ADP_GLC_PYROPHOSPH_2; 1;
PS00810; ADP_GLC_PYROPHOSPH_3; 1;

Additional information [?]

Size range 376-476 amino acids
Related rules None
Templates P0A6V1 (GLGC_ECOLI); P30521 (GLGC_NOSS1); P9WN43 (GLGC_MYCTU): [Recover all]
Fusion None
Comments GlgC from M.tuberculosis is involved in the biosynthesis of both glycogen and capsular alpha-D-glucan.