HAMAP

Accession	MF_00637
Dates	17-APR-2003 (Created) 29-MAR-2011 (Last updated, Version 14)

Data class

Protein

Predictors

HAMAP; MF_00637; [distribution of match scores in UniProtKB];[seed alignment for MF_00637]

Names

Anti_sigma_F

Identifier

SP2AB

Protein name

RecName: Full=Anti-sigma F factor; EC=2.7.11.1; AltName: Full=Stage II sporulation protein AB;

Gene name

spoIIAB

FUNCTION: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity).

CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.

SIMILARITY: Belongs to the anti-sigma-factor family.

Pfam	PF02518; HATPase_c; 1;

ATP-binding, Kinase, Nucleotide-binding, Sporulation, Transferase.

GO:0004672; Molecular function: protein kinase activity.
GO:0010468; Biological process: regulation of gene expression.
GO:0030436; Biological process: asexual sporulation.

Size range:	140-151 amino acids
Related UniRules:	MF_00638 (RSBW)
Template:	P10728 (SP2AB_BACSU)
Scope:	Bacteria; Bacillales Bacteria; Clostridia
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None