Annotation rule MF_00638
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General rule information [?]

Accession MF_00638
Dates 17-APR-2003 (Created)
15-NOV-2012 (Last updated, Version 14)
Name Anti_sigma_B
Scope Bacteria; Bacillales
Template P17904 (RSBW_BACSU)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
RSBW
Protein name
RecName: Full=Serine-protein kinase RsbW;
EC=2.7.11.1;
AltName: Full=Anti-sigma-B factor;
AltName: Full=Sigma-B negative effector RsbW;
Gene name
rsbW

Comments [?]

Function Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B) (By similarity).
Catalytic activity ATP + a protein = ADP + a phosphoprotein.
Similarity Belongs to the anti-sigma-factor family.

Keywords [?]


Gene Ontology [?]

GO:0004672; Molecular function: protein kinase activity.
GO:0010468; Biological process: regulation of gene expression.

Cross-references [?]

Pfam PF02518; HATPase_c; 1;

Additional information [?]

Size range 157-162 amino acids
Related rules MF_00637 (SP2AB)
Fusion None