HAMAP rule MF_00647
General rule information
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Accession | MF_00647 |
Dates | 4-JUN-2003 (Created)
1-JUN-2023 (Last updated, Version 28) |
Name | PPAT_arch |
Scope(s) |
Archaea |
Template(s) | Q9UYT0 (COAD_PYRAB); [ Recover all ] |
Triggered by |
HAMAP; MF_00647 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | COAD |
Protein name | RecName: Full=Phosphopantetheine adenylyltransferase; EC=2.7.7.3; AltName: Full=Dephospho-CoA pyrophosphorylase; AltName: Full=Pantetheine-phosphate adenylyltransferase; Short=PPAT; |
Gene name | Name=coaD; |
Comments
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FUNCTION | Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. |
CATALYTIC ACTIVITY | Reaction=(R)-4'-phosphopantetheine + ATP + H(+) = 3'-dephospho-CoA + diphosphate; Xref=Rhea:RHEA:19801, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:57328, ChEBI:CHEBI:61723; EC=2.7.7.3; |
PATHWAY | Cofactor biosynthesis; coenzyme A biosynthesis. |
SUBCELLULAR LOCATION | Cytoplasm. |
SIMILARITY | Belongs to the eukaryotic CoaD family. |
Keywords
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Gene Ontology
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GO:0004595; Molecular function:pantetheine-phosphate adenylyltransferase activity |
GO:0015937; Biological process:coenzyme A biosynthetic process |
GO:0005737; Cellular component:cytoplasm |
Cross-references
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Features
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Additional information
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Size range | 147-165 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: MF_00648 (yjjX) |