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| HAMAP annotation rule MF_00649 |
| Accession | MF_00649 |
| Dates | 4-JUN-2003 (Created) 12-AUG-2011 (Last updated, Version 20) |
| Name | DNA_gyrase_inhibitor_YacG |
| Scope | Bacteria; Proteobacteria Bacteria; Planctomycetes |
| Triggered by |
| Identifier |
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| Protein name |
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| FUNCTION | Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity). |
case <FTGroup:1>
| COFACTOR | Binds 1 zinc ion (By similarity). |
end case
| SUBUNIT | Interacts with GyrB (By similarity). |
| SIMILARITY | Belongs to the DNA gyrase inhibitor YacG family. |
case <FTGroup:1>
end case
GO:0008657; Molecular function: DNA topoisomerase (ATP-hydrolyzing) inhibitor activity.
case <FTGroup:1>
GO:0008270; Molecular function: zinc ion binding.
end case
| Pfam | PF03884; DUF329; 1; |
| From: YACG_ECOLI (P0A8H8) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| METAL | 9 | 9 | Zinc (By similarity) | C | 1 | |||||||
| METAL | 12 | 12 | Zinc (By similarity) | C | 1 | |||||||
| METAL | 28 | 28 | Zinc (By similarity) | C | 1 | |||||||
| METAL | 32 | 32 | Zinc (By similarity) | C | 1 | |||||||
| Size range: | 48-82 amino acids |
| Related Rules: | None |
| Template: | P0A8H8 (YACG_ECOLI) |
| Fusion: | None |