HAMAP

Accession	MF_00649
Dates	4-JUN-2003 (Created) 12-AUG-2011 (Last updated, Version 20)

Data class

Protein

Predictors

HAMAP; MF_00649; [distribution of match scores in UniProtKB];[seed alignment for MF_00649]

Names

DNA_gyrase_inhibitor_YacG

Identifier

YACG

Protein name

RecName: Full=DNA gyrase inhibitor YacG;

Gene name

yacG

FUNCTION: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity).

COFACTOR: Binds 1 zinc ion (By similarity).

SUBUNIT: Interacts with GyrB (By similarity).

SIMILARITY: Belongs to the DNA gyrase inhibitor YacG family.

Pfam	PF03884; DUF329; 1;

Zinc, Metal-binding.

GO:0008657; Molecular function: DNA topoisomerase (ATP-hydrolyzing) inhibitor activity.

GO:0008270; Molecular function: zinc ion binding.

From: YACG_ECOLI (P0A8H8)
Key		From		To		Description		Condition		FTGroup
METAL		9		9		Zinc (By similarity)		C		1
METAL		12		12		Zinc (By similarity)		C		1
METAL		28		28		Zinc (By similarity)		C		1
METAL		32		32		Zinc (By similarity)		C		1

Size range:	48-82 amino acids
Related UniRules:	None
Template:	P0A8H8 (YACG_ECOLI)
Scope:	Bacteria; Proteobacteria Bacteria; Planctomycetes
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None