HAMAP

Accession	MF_00658
Dates	17-JUN-2003 (Created) 10-NOV-2011 (Last updated, Version 26)

Data class

Protein

Predictors

HAMAP; MF_00658; [distribution of match scores in UniProtKB];[seed alignment for MF_00658]

Names

23SrRNA_methyltr_H

Identifier

RLMH

Protein name

RecName: Full=Ribosomal RNA large subunit methyltransferase H; EC=2.1.1.177; AltName: Full=23S rRNA (pseudouridine1915-N3)-methyltransferase; AltName: Full=23S rRNA m3Psi1915 methyltransferase; AltName: Full=rRNA (pseudouridine-N3-)-methyltransferase RlmH;

Protein name

RecName: Full=Putative ribosomal RNA large subunit methyltransferase H; EC=2.1.1.177; AltName: Full=23S rRNA (pseudouridine1915-N3)-methyltransferase; AltName: Full=rRNA (pseudouridine-N3-)-methyltransferase RlmH;

Gene name

rlmH

FUNCTION: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity).

CATALYTIC ACTIVITY: S-adenosyl-L-methionine + pseudouridine(1915) in 23S rRNA = S-adenosyl-L-homocysteine + N(3)-methylpseudouridine(1915) in 23S rRNA.

SUBUNIT: Homodimer (By similarity).

SUBCELLULAR LOCATION: Cytoplasm (Potential).

SIMILARITY: Belongs to the RNA methyltransferase RlmH family.

Pfam	PF02590; SPOUT_MTase; 1;
PIRSF	PIRSF004505; MT_bac; 1;
TIGRFAMs	TIGR00246; TRNA_RlmH_YbeA; 1;

Cytoplasm, Methyltransferase, rRNA processing, S-adenosyl-L-methionine, Transferase.

GO:0070038; Molecular function: rRNA (pseudouridine-N3-)-methyltransferase activity.
GO:0031167; Biological process: rRNA methylation.
GO:0005737; Cellular component: cytoplasm.

Size range:	133-174 amino acids
Related UniRules:	None
Template:	P0A8I8 (RLMH_ECOLI)
Scope:	Bacteria Archaea; Euryarchaeota
Fusion:	Nter: None; Cter: None
Duplicate:	in CLOPS, ECODH, THEP3, THEPX, THETN
Plasmid encoded:	None