HAMAP

Accession	MF_00661
Dates	26-JUN-2003 (Created) 1-JUN-2010 (Last updated, Version 16)

Data class

Protein

Predictors

HAMAP; MF_00661; [distribution of match scores in UniProtKB];[seed alignment for MF_00661]

Names

Helicase_RhlB

Identifier

RHLB

Protein name

RecName: Full=ATP-dependent RNA helicase rhlB; EC=3.6.4.13;

Gene name

rhlB

FUNCTION: Can carry out ATP-dependent unwinding of double stranded RNA. Has a role in RNA decay. Involved in the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation (By similarity).

CATALYTIC ACTIVITY: ATP + H(2)O = ADP + phosphate.

SUBUNIT: Component of the degradosome complex (By similarity).

SIMILARITY: Belongs to the DEAD box helicase family.

SIMILARITY: Contains 1 helicase ATP-binding domain.

SIMILARITY: Contains 1 helicase C-terminal domain.

Pfam	PF00270; DEAD; 1; PF00271; Helicase_C; 1;
PROSITE	PS00039; DEAD_ATP_HELICASE; 1; PS51192; HELICASE_ATP_BIND_1; 1; trigger=PRU00541; PS51194; HELICASE_CTER; 1; trigger=PRU00542; PS51195; Q_MOTIF; 1; trigger=PRU00552;

Hydrolase, Helicase, ATP-binding, Nucleotide-binding, RNA-binding.

GO:0005524; Molecular function: ATP binding.
GO:0016818; Molecular function: hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides.
GO:0003724; Molecular function: RNA helicase activity.
GO:0006401; Biological process: RNA catabolic process.

From: RHLB_ECOLI (P0A8J8)
Key		From		To		Description		Condition		FTGroup
NP_BIND		53		60		ATP (By similarity)		A-Q-T-G-T-G-K-T
MOTIF		165		168		DEAD box		D-E-A-D

Size range:	397-573 amino acids
Related UniRules:	None
Template:	P0A8J8 (RHLB_ECOLI)
Scope:	Bacteria; Gammaproteobacteria
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None