HAMAP

Accession	MF_00668
Dates	7-JUL-2003 (Created) 10-OCT-2011 (Last updated, Version 20)

Data class

Protein

Predictors

HAMAP; MF_00668; [distribution of match scores in UniProtKB];[seed alignment for MF_00668]

Names

BioW

Identifier

BIOW

Protein name

RecName: Full=6-carboxyhexanoate--CoA ligase; EC=6.2.1.14; AltName: Full=Pimeloyl-CoA synthase;

Gene name

bioW

FUNCTION: Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP (By similarity).

CATALYTIC ACTIVITY: ATP + 6-carboxyhexanoate + CoA = AMP + diphosphate + 6-carboxyhexanoyl-CoA.

COFACTOR: Magnesium (By similarity).

PATHWAY: Metabolic intermediate metabolism; pimeloyl-CoA biosynthesis; pimeloyl-CoA from pimelate: step 1/1.

SUBUNIT: Homodimer (By similarity).

SIMILARITY: Belongs to the BioW family.

Pfam	PF03744; BioW; 1;
TIGRFAMs	TIGR01204; BioW; 1;

ATP-binding, Biotin biosynthesis, Ligase, Magnesium, Nucleotide-binding.

GO:0042410; Molecular function: 6-carboxyhexanoate-CoA ligase activity.
GO:0000287; Molecular function: magnesium ion binding.
GO:0009102; Biological process: biotin biosynthetic process.

Size range:	228-259 amino acids
Related UniRules:	None
Template:	P22822 (BIOW_LYSSH)
Scope:	Bacteria Archaea
Fusion:	Nter: None; Cter: MF_01693 (bioF)
Duplicate:	None
Plasmid encoded:	None