Annotation rule MF_00679
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General rule information [?]

Accession MF_00679
Dates 16-JUL-2003 (Created)
13-APR-2012 (Last updated, Version 16)
Name HscA
Scope Bacteria

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
HSCA
case <OC:Enterobacteriaceae>
Protein name
RecName: Full=Chaperone protein HscA;
AltName: Full=Hsc66;
end case
case not <OC:Enterobacteriaceae>
Protein name
RecName: Full=Chaperone protein HscA homolog;
end case
Gene name
hscA

Comments [?]

case <OC:Enterobacteriaceae>
Function Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU (By similarity).
end case
case not <OC:Enterobacteriaceae>
Function Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB (By similarity).
end case
Similarity Belongs to the heat shock protein 70 family.

Keywords [?]


Gene Ontology [?]

GO:0016887; Molecular function: ATPase activity.
GO:0006457; Biological process: protein folding.

Cross-references [?]

Pfam PF00012; HSP70; 1;
PRINTS PR00301; HEATSHOCK70; 1;
PROSITE PS00297; HSP70_1; 1;
PS00329; HSP70_2; 1;
PS01036; HSP70_3; 1;

Additional information [?]

Size range 586-622 amino acids
Related rules MF_00332 (DNAK)
Template P0A6Z1 (HSCA_ECOLI)
Fusion None
Comments Divergent YERPE and YERPS with insert not shown in alignment or taken in size range