HAMAP

Accession	MF_00685
Dates	18-AUG-2003 (Created) 10-OCT-2011 (Last updated, Version 24)

Data class

Protein

Predictors

HAMAP; MF_00685; [distribution of match scores in UniProtKB];[seed alignment for MF_00685]

Names

GlgB

Identifier

GLGB

Protein name

RecName: Full=1,4-alpha-glucan branching enzyme GlgB; EC=2.4.1.18; AltName: Full=1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase; AltName: Full=Alpha-(1->4)-glucan branching enzyme; AltName: Full=Glycogen branching enzyme; Short=BE;

Gene name

glgB

FUNCTION: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity).

CATALYTIC ACTIVITY: Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.

PATHWAY: Glycan biosynthesis; glycogen biosynthesis.

SUBUNIT: Monomer (By similarity).

SIMILARITY: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

Pfam	PF00128; Alpha-amylase; 1; PF02806; Alpha-amylase_C; 1; PF02922; CBM_48; 1;
TIGRFAMs	TIGR01515; Branching_enzym; 1;

Carbohydrate metabolism, Glycogen biosynthesis, Glycogen metabolism, Glycosyltransferase, Transferase.

GO:0003844; Molecular function: 1,4-alpha-glucan branching enzyme activity.
GO:0005978; Biological process: glycogen biosynthetic process.

From: GLGB_MYCTU (Q10625)
Key		From		To		Description		Condition		FTGroup
ACT_SITE		411		411		Nucleophile (By similarity)		D
ACT_SITE		464		464		Proton donor (By similarity)		E

Size range:	611-838 amino acids
Related UniRules:	None
Template:	P07762 (GLGB_ECOLI); Q10625 (GLGB_MYCTU); Q8GQC5 (GLGB_ERWCH): [Recover all]
Scope:	Bacteria Archaea; Thermoplasmata
Fusion:	Nter: None; Cter: None
Duplicate:	in CLOPE, CLOPS, RHIEC, RHIL3, STRAW, STRCO, XANAC, XANC5, XANC8, XANCP, XANOM, XANOR
Plasmid encoded:	in RALSO
Comments:	GlgB from M.tuberculosis is involved in the biosynthesis of both glycogen and capsular alpha-D-glucan.