HAMAP

Accession	MF_00688
Dates	24-JUL-2003 (Created) 10-OCT-2011 (Last updated, Version 17)

Data class

Protein

Predictors

HAMAP; MF_00688; [distribution of match scores in UniProtKB];[seed alignment for MF_00688]

Names

Leu_Phe_trans

Identifier

LFTR

Protein name

RecName: Full=Leucyl/phenylalanyl-tRNA--protein transferase; EC=2.3.2.6; AltName: Full=L/F-transferase; AltName: Full=Leucyltransferase; AltName: Full=Phenyalanyltransferase;

Gene name

aat

FUNCTION: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity).

CATALYTIC ACTIVITY: L-leucyl-tRNA + protein = tRNA + L-leucyl-protein.

CATALYTIC ACTIVITY: L-phenylalanyl-tRNA + protein = tRNA + L-phenylalanyl-protein.

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the L/F-transferase family.

Pfam	PF03588; Leu_Phe_trans; 1;
TIGRFAMs	TIGR00667; Aat; 1;

Cytoplasm, Transferase, Acyltransferase.

GO:0008914; Molecular function: leucyltransferase activity.
GO:0030163; Biological process: protein catabolic process.
GO:0005737; Cellular component: cytoplasm.

Size range:	191-274 amino acids
Related UniRules:	None
Template:	P0A8P1 (LFTR_ECOLI)
Scope:	Bacteria
Fusion:	Nter: None; Cter: None
Duplicate:	in RHOPB
Plasmid encoded:	None