HAMAP rule MF_00698
General rule information
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Accession | MF_00698 |
Dates | 22-AUG-2003 (Created)
18-NOV-2019 (Last updated, Version 18) |
Name | Aminopeptidase_S15 |
Scope(s) |
Bacteria Lactobacillales |
Template(s) | P22346 (PEPX_LACLC); Q93M42 (PEPX_STRGN); [ Recover all ] |
Triggered by |
HAMAP; MF_00698 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | PEPX |
Protein name | RecName: Full=Xaa-Pro dipeptidyl-peptidase; EC=3.4.14.11; AltName: Full=X-Pro dipeptidyl-peptidase; AltName: Full=X-prolyl-dipeptidyl aminopeptidase; Short=X-PDAP; |
Gene name | Name=pepX; |
Comments
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FUNCTION | Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline. |
CATALYTIC ACTIVITY | Reaction=Hydrolyzes Xaa-Pro-|- bonds to release unblocked, N-terminal dipeptides from substrates including Ala-Pro-|-p-nitroanilide and (sequentially) Tyr-Pro-|-Phe-Pro-|-Gly-Pro-|-Ile.; EC=3.4.14.11; |
SUBUNIT | Homodimer. |
SUBCELLULAR LOCATION | Cytoplasm. |
SIMILARITY | Belongs to the peptidase S15 family. |
Keywords
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Gene Ontology
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GO:0008239; Molecular function:dipeptidyl-peptidase activity |
GO:0005737; Cellular component:cytoplasm |
Cross-references
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Features
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From: PEPX_LACLC (P22346) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
ACT_SITE | 348 | 348 | /note="Charge relay system" | S | ||||||||
ACT_SITE | 468 | 468 | /note="Charge relay system" | D | ||||||||
ACT_SITE | 498 | 498 | /note="Charge relay system" | H |
Additional information
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Size range | 755-813 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |