 |
|
|||||||
| HAMAP annotation rule: MF_00706 |
| Accession | MF_00706 |
| Dates | 1-SEP-2003 (Created) 22-OCT-2010 (Last updated, Version 21) |
| Data class | Protein |
| Predictors | HAMAP; MF_00706; [distribution of match scores in UniProtKB];[seed alignment for MF_00706] |
| Names | Ecotin |
| Identifier | ECOT |
| Protein name |
|
| Gene name | eco |
case <OC:Enterobacteriaceae>
FUNCTION: General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases (By similarity).
end case
case not <OC:Enterobacteriaceae>
FUNCTION: General inhibitor of family S1 serine proteases (By similarity).
end case
SUBUNIT: Homodimer (By similarity).
SUBCELLULAR LOCATION: Periplasm (By similarity).
SIMILARITY: Belongs to the protease inhibitor I11 (ecotin) family.
| Pfam |
PF03974; Ecotin; 1; |
| General |
Signal; -; 1; trigger=Yes; |
case <FT:2>
end case
GO:0004867; Molecular function: serine-type endopeptidase inhibitor activity.
GO:0042597; Cellular component: periplasmic space.
GO:0042597; Cellular component: periplasmic space.
| From: ECOT_ECOLI (P23827) | ||||||||||
| Key | From | To | Description | Condition | FTGroup | |||||
| SITE | 104 | 105 | Reactive bond (By similarity) | x-M | ||||||
| DISULFID | 70 | 107 | By similarity | C-x*-C | ||||||
| Size range: | 156-183 amino acids |
| Related UniRules: | None |
| Template: | P23827 (ECOT_ECOLI) |
| Scope: | Bacteria |
| Fusion: | Nter: None; Cter: None |
| Duplicate: | None |
| Plasmid encoded: | None |
View rule in raw text format (no links)