| FUNCTION |
The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (By similarity). |
| CATALYTIC ACTIVITY |
Glycine + H-protein-lipoyllysine = H-protein-S-aminomethyldihydrolipoyllysine + CO(2). |
| COFACTOR |
Pyridoxal phosphate (By similarity). |
| SUBUNIT |
The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits (By similarity). |
| SIMILARITY |
Belongs to the GcvP family. C-terminal subunit subfamily. |
