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HAMAP rule MF_00714

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General rule information [?]

Accession MF_00714
Dates 25-SEP-2003 (Created)
18-NOV-2019 (Last updated, Version 17)
Name MerB
Scope(s) Bacteria
Template(s) P08653 (MERB_STAAU); [ Recover all ]
Triggered by HAMAP; MF_00714 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier MERB
Protein name RecName: Full=Alkylmercury lyase;
                 EC=4.99.1.2;
AltName: Full=Organomercurial lyase;
Gene name Name=merB;

Comments [?]

FUNCTIONCleaves the carbon-mercury bond of organomercurials such as phenylmercuric acetate. One product is Hg(2+), which is subsequently detoxified by the mercuric reductase.
CATALYTIC ACTIVITY Reaction=an alkylmercury + H(+) = an alkane + Hg(2+); Xref=Rhea:RHEA:18777, ChEBI:CHEBI:15378, ChEBI:CHEBI:16793, ChEBI:CHEBI:18310, ChEBI:CHEBI:83725; EC=4.99.1.2;
SIMILARITYBelongs to the MerB family.

Keywords [?]


Gene Ontology [?]

GO:0046689; Biological process:response to mercury ion
GO:0018836; Molecular function:alkylmercury lyase activity

Cross-references [?]

Pfam PF03243; MerB; 1;
PRINTS PR01699; ORGNOHGLYASE; 1;

Features [?]


Additional information [?]

Size range 212-218 amino acids
Related rules None
Fusion Nter: None Cter: None



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