Annotation rule MF_00716
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General rule information [?]

Accession MF_00716
Dates 2-OCT-2003 (Created)
10-SEP-2012 (Last updated, Version 31)
Name NosZ
Scope Bacteria
Templates Q51705 (NOSZ_PARDE); P19573 (NOSZ_PSEST): [Recover all]

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
NOSZ
Protein name
RecName: Full=Nitrous-oxide reductase;
EC=1.7.2.4;
AltName: Full=N(2)OR;
AltName: Full=N2O reductase;
Flags: Precursor;
Gene name
nosZ

Comments [?]

Function Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide (By similarity).
Catalytic activity Nitrogen + H(2)O + 2 ferricytochrome c = nitrous oxide + 2 ferrocytochrome c + 2 H(+).
Cofactor Binds 2 calcium ions per subunit (By similarity).
Binds 6 copper ions per subunit. Each subunit contains 2 copper centers; Cu(A) (binuclear) and Cu(Z) (tetranuclear). Cu(Z) is thought to be the site of nitrous oxide reduction (By similarity).
Subunit Homodimer (By similarity).
Subcellular location Periplasm (By similarity).
case <Feature:PS51318>
Ptm Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.
end case
Similarity Belongs to the NosZ family.
In the C-terminal section; belongs to the cytochrome c oxidase subunit 2 family.

Keywords [?]


Gene Ontology [?]

GO:0005509; Molecular function: calcium ion binding.
GO:0005507; Molecular function: copper ion binding.
GO:0050304; Molecular function: nitrous-oxide reductase activity.
GO:0042597; Cellular component: periplasmic space.

Cross-references [?]

Pfam PF00394; Cu-oxidase; 1;
TIGRFAMs TIGR01409; TAT_signal_seq; 1;
PROSITE PS00078; COX2; 1;
PS51318; TAT; 0-1; trigger=PRU00648;

Computed features [?]

case not <Feature:PS51318>
General Signal; -; 1; trigger=yes;
end case

Features [?]

From: NOSZ_PARDE (Q51705)
Key     From     To       Description   Tag   Condition   FTGroup
REGION     554     Cter       COX2-like        
METAL     145     145       Copper Z2 (By similarity)     H   1
METAL     146     146       Copper Z3 (By similarity)     H   1
METAL     194     194       Copper Z2 (By similarity)     H   1
METAL     271     271       Calcium 2; via carbonyl oxygen (By similarity)     Y   3
METAL     274     274       Calcium 2 (By similarity)     E   3
METAL     282     282       Calcium 2; via carbonyl oxygen (By similarity)     M   3
METAL     288     288       Calcium 2 (By similarity)     D   3
METAL     335     335       Calcium 2 (By similarity)     [NS]   3
METAL     337     337       Copper Z1 (By similarity)     H   1
METAL     392     392       Copper Z1 (By similarity)     H   1
METAL     443     443       Copper Z3 (By similarity)     H   1
METAL     464     464       Calcium 1; via carbonyl oxygen (By similarity)     K   3
METAL     479     479       Calcium 1 (By similarity)     E   3
METAL     504     504       Copper Z4 (By similarity)     H   1
METAL     595     595       Copper A1 (By similarity)     H   2
METAL     630     630       Copper A1 (By similarity)     C   2
METAL     630     630       Copper A2 (By similarity)     C   2
METAL     632     632       Copper A2; via carbonyl oxygen (By similarity)     [WH]   2
METAL     634     634       Copper A1 (By similarity)     C   2
METAL     634     634       Copper A2 (By similarity)     C   2
METAL     638     638       Copper A2 (By similarity)     H   2
METAL     641     641       Copper A1 (By similarity)     M   2

Additional information [?]

Size range 634-652 amino acids
Related rules None
Fusion None