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HAMAP rule MF_00729

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General rule information [?]

Accession MF_00729
Dates 20-NOV-2003 (Created)
18-NOV-2019 (Last updated, Version 23)
Name FBP_aldolase_1
Scope(s) Bacteria
Template(s) Q07159 (ALF1_STACT); [ Recover all ]
Triggered by HAMAP; MF_00729 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier ALF1
Protein name RecName: Full=Fructose-bisphosphate aldolase class 1;
                 EC=4.1.2.13;
AltName: Full=Fructose-bisphosphate aldolase class I;
                 Short=FBP aldolase;
Gene name Name=fda;

Comments [?]

CATALYTIC ACTIVITY Reaction=beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3- phosphate + dihydroxyacetone phosphate; Xref=Rhea:RHEA:14729, ChEBI:CHEBI:32966, ChEBI:CHEBI:57642, ChEBI:CHEBI:59776; EC=4.1.2.13;
PATHWAYCarbohydrate degradation; glycolysis; D-glyceraldehyde 3- phosphate and glycerone phosphate from D-glucose: step 4/4.
SIMILARITYBelongs to the class I fructose-bisphosphate aldolase family.

Keywords [?]


Gene Ontology [?]

GO:0004332; Molecular function:fructose-bisphosphate aldolase activity
GO:0006096; Biological process:glycolytic process

Cross-references [?]

Pfam PF00274; Glycolytic; 1;
PROSITE PS00158; ALDOLASE_CLASS_I; 1;

Features [?]

From: ALF1_STACT (Q07159)
Key From To Description Tag Condition FTGroup
ACT_SITE 175 175 /note="Proton acceptor" E
ACT_SITE 212 212 /note="Schiff-base intermediate with dihydroxyacetone-P" K

Additional information [?]

Size range 293-300 amino acids
Related rules None
Fusion Nter: None Cter: None



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