HAMAP

Accession	MF_00731
Dates	20-NOV-2003 (Created) 10-OCT-2011 (Last updated, Version 22)

Data class

Protein

Predictors

HAMAP; MF_00731; [distribution of match scores in UniProtKB];[seed alignment for MF_00731]

Names

MenE

Identifier

MENE

Protein name

RecName: Full=2-succinylbenzoate--CoA ligase; EC=6.2.1.26; AltName: Full=OSB-CoA synthetase; AltName: Full=o-succinylbenzoyl-CoA synthetase;

Gene name

menE

FUNCTION: Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA) (By similarity).

CATALYTIC ACTIVITY: ATP + 2-succinylbenzoate + CoA = AMP + diphosphate + 2-succinylbenzoyl-CoA.

PATHWAY: Cofactor biosynthesis; menaquinone biosynthesis; menaquinone-2 from chorismate: step 5/8.

SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.

Pfam	PF00501; AMP-binding; 1;
PRINTS	PR00154; AMPBINDING; 1;
TIGRFAMs	TIGR01923; MenE; 1; TIGR01733; AA-adenyl-dom; 1;
PROSITE	PS00455; AMP_BINDING; 1;

ATP-binding, Ligase, Menaquinone biosynthesis, Nucleotide-binding.

GO:0008756; Molecular function: o-succinylbenzoate-CoA ligase activity.
GO:0009234; Biological process: menaquinone biosynthetic process.

Size range:	451-492 amino acids
Related UniRules:	None
Template:	P23971 (MENE_BACSU)
Scope:	Bacteria; Bacillales Bacteria; Lactobacillales
Fusion:	Nter: None; Cter: None
Duplicate:	in STAAU
Plasmid encoded:	None