HAMAP

Accession	MF_00737
Dates	25-NOV-2003 (Created) 10-OCT-2011 (Last updated, Version 16)

Data class

Protein

Predictors

HAMAP; MF_00737; [distribution of match scores in UniProtKB];[seed alignment for MF_00737]

Names

Formimidoylglutam

Identifier

HUTG

Protein name

RecName: Full=Formimidoylglutamase; EC=3.5.3.8; AltName: Full=Formiminoglutamase; AltName: Full=Formiminoglutamate hydrolase;

Gene name

hutG

CATALYTIC ACTIVITY: N-formimidoyl-L-glutamate + H(2)O = L-glutamate + formamide.

COFACTOR: Binds 2 manganese ions per subunit (By similarity).

PATHWAY: Amino-acid degradation; L-histidine degradation into L-glutamate; L-glutamate from N-formimidoyl-L-glutamate (hydrolase route): step 1/1.

SIMILARITY: Belongs to the arginase family.

Pfam	PF00491; Arginase; 1;
PRINTS	PR00116; ARGINASE; 1;
TIGRFAMs	TIGR01227; HutG; 1;
PROSITE	PS01053; ARGINASE_1; 1; PS51409; ARGINASE_2; 1;

Hydrolase, Histidine metabolism.

Metal-binding, Manganese.

GO:0050415; Molecular function: formimidoylglutamase activity.
GO:0030145; Molecular function: manganese ion binding.
GO:0006548; Biological process: histidine catabolic process.

From: HUTG_BACSU (P42068)
Key		From		To		Description		Condition		FTGroup
METAL		127		127		Manganese 1 (By similarity)		[HN]		1
METAL		150		150		Manganese 1 (By similarity)		D		1
METAL		150		150		Manganese 2 (By similarity)		D		1
METAL		152		152		Manganese 2 (By similarity)		H		1
METAL		154		154		Manganese 1 (By similarity)		D		1
METAL		242		242		Manganese 1 (By similarity)		[DC]		1
METAL		242		242		Manganese 2 (By similarity)		[DC]		1
METAL		244		244		Manganese 2 (By similarity)		D		1

Size range:	306-364 amino acids
Related UniRules:	None
Template:	P42068 (HUTG_BACSU)
Scope:	Bacteria Archaea; Halobacteria
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None