HAMAP

Accession	MF_00740
Dates	26-NOV-2003 (Created) 10-OCT-2011 (Last updated, Version 22)

Data class

Protein

Predictors

HAMAP; MF_00740; [distribution of match scores in UniProtKB];[seed alignment for MF_00740]

Names

Phosphopentomut

Identifier

DEOB

Protein name

RecName: Full=Phosphopentomutase; EC=5.4.2.7; AltName: Full=Phosphodeoxyribomutase;

Gene name

deoB

FUNCTION: Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity).

CATALYTIC ACTIVITY: Alpha-D-ribose 1-phosphate = D-ribose 5-phosphate.

CATALYTIC ACTIVITY: 2-deoxy-alpha-D-ribose 1-phosphate = 2-deoxy-alpha-D-ribose 5-phosphate.

PATHWAY: Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route II): step 1/3.

COFACTOR: Binds 1 or 2 manganese ions (Potential).

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the phosphopentomutase family.

Pfam	PF01676; Metalloenzyme; 1;
TIGRFAMs	TIGR01696; DeoB; 1;

Acetylation.

Cytoplasm, Isomerase.

Metal-binding, Manganese.

GO:0030145; Molecular function: manganese ion binding.
GO:0008973; Molecular function: phosphopentomutase activity.
GO:0009264; Biological process: deoxyribonucleotide catabolic process.
GO:0009166; Biological process: nucleotide catabolic process.
GO:0005737; Cellular component: cytoplasm.

From: DEOB_ECOLI (P0A6K6)
Key		From		To		Description		Condition		FTGroup
METAL		10		10		Manganese (By similarity)		D		1
METAL		311		311		Manganese (By similarity)		H		1
METAL		347		347		Manganese (By similarity)		D		1
METAL		348		348		Manganese (By similarity)		H		1
METAL		359		359		Manganese (By similarity)		H		1

Key		From		To		Description		Condition		FTGroup
MOD_RES		287		287		N6-acetyllysine (By similarity)		K

Size range:	388-418 amino acids
Related UniRules:	None
Template:	P0A6K6 (DEOB_ECOLI)
Scope:	Bacteria
Fusion:	Nter: None; Cter: None
Duplicate:	in STRA1
Plasmid encoded:	None