HAMAP

Accession	MF_00744
Dates	10-DEC-2003 (Created) 30-MAY-2011 (Last updated, Version 16)

Data class

Protein

Predictors

HAMAP; MF_00744; [distribution of match scores in UniProtKB];[seed alignment for MF_00744]

Names

MetJ

Identifier

METJ

Protein name

RecName: Full=Met repressor; AltName: Full=Met regulon regulatory protein metJ;

Gene name

metJ

FUNCTION: This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity).

SUBUNIT: Homodimer (By similarity).

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

DOMAIN: Does not bind DNA by an helix-turn-helix motif.

SIMILARITY: Belongs to the metJ family.

Pfam	PF01340; MetJ; 1;

Cytoplasm, Amino-acid biosynthesis, Transcription, Transcription regulation, Repressor, Methionine biosynthesis, DNA-binding.

GO:0045892; Biological process: negative regulation of transcription, DNA-dependent.
GO:0009086; Biological process: methionine biosynthetic process.
GO:0005737; Cellular component: cytoplasm.

Size range:	104-106 amino acids
Related UniRules:	None
Template:	P0A8U6 (METJ_ECOLI)
Scope:	Bacteria; Proteobacteria
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None