HAMAP

Accession	MF_00767
Dates	6-APR-2004 (Created) 11-OCT-2011 (Last updated, Version 18)

Data class

Protein

Predictors

HAMAP; MF_00767; [distribution of match scores in UniProtKB];[seed alignment for MF_00767]

Names

Arg_catab_AstE

Identifier

ASTE

Protein name

RecName: Full=Succinylglutamate desuccinylase; EC=3.5.1.96;

Gene name

astE

FUNCTION: Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity).

CATALYTIC ACTIVITY: N-succinyl-L-glutamate + H(2)O = succinate + L-glutamate.

COFACTOR: Binds 1 zinc ion per subunit (By similarity).

PATHWAY: Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 5/5.

SIMILARITY: Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.

Pfam	PF04952; AstE_AspA; 1;
PIRSF	PIRSF017020; AstE; 1;
TIGRFAMs	TIGR03242; Arg_catab_astE; 1;

Arginine metabolism, Hydrolase.

Zinc, Metal-binding.

GO:0016788; Molecular function: hydrolase activity, acting on ester bonds.

GO:0008270; Molecular function: zinc ion binding.

GO:0019544; Biological process: arginine catabolic process to glutamate.

From: ASTE_CHRVO (Q7NU26)
Key		From		To		Description		Condition		FTGroup
ACT_SITE		214		214		Potential		E
METAL		56		56		Zinc (By similarity)		H		1
METAL		59		59		Zinc (By similarity)		E		1
METAL		149		149		Zinc (By similarity)		H		1

Size range:	322-351 amino acids
Related UniRules:	None
Template:	P76215 (ASTE_ECOLI); Q7NU26 (ASTE_CHRVO); Q87Q40 (ASTE_VIBPA): [Recover all]
Scope:	Bacteria; Proteobacteria
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None