HAMAP

Accession	MF_00784
Dates	18-MAY-2004 (Created) 2-JUL-2010 (Last updated, Version 17)

Data class

Protein

Predictors

HAMAP; MF_00784; [distribution of match scores in UniProtKB];[seed alignment for MF_00784]

Names

AgrB

Identifier

AGRB

Protein name

RecName: Full=Accessory gene regulator protein B; EC=3.4.-.-;

Gene name

agrB

Protein name

RecName: Full=Putative AgrB-like protein; EC=3.4.-.-;

FUNCTION: Essential for the production of a quorum sensing system signal molecule, the autoinducing peptide (AIP). This quorum sensing system is responsible for the regulation of the expression of virulence factor genes. Involved in the proteolytic processing of AgrD, the precursor of AIP (By similarity).

FUNCTION: May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor (Potential).

SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein (Potential).

SIMILARITY: Belongs to the AgrB family.

Pfam	PF04647; AgrB; 1;
General	Transmembrane; -; 3-5; trigger=Yes;

Cell membrane, Membrane, Hydrolase, Protease, Quorum sensing, Transmembrane.

Virulence.

Transmembrane helix.

GO:0008233; Molecular function: peptidase activity.
GO:0009372; Biological process: quorum sensing.
GO:0005886; Cellular component: plasma membrane.

Size range:	187-242 amino acids
Related UniRules:	None
Template:	P0C1P7 (AGRB_STAAU)
Scope:	Bacteria; Firmicutes
Fusion:	Nter: None; Cter: None
Duplicate:	in CLOPE
Plasmid encoded:	None