HAMAP

Accession	MF_00786
Dates	24-MAY-2004 (Created) 11-JUN-2010 (Last updated, Version 15)

Data class

Protein

Predictors

HAMAP; MF_00786; [distribution of match scores in UniProtKB];[seed alignment for MF_00786]

Names

CbiT

Identifier

CBIT

Protein name

RecName: Full=Probable cobalt-precorrin-6Y C(15)-methyltransferase [decarboxylating]; EC=2.1.1.-;

Gene name

cbiT

FUNCTION: Probably catalyzes the methylation of either C-15 or C-5 in cobalt-precorrin-6Y to form cobalt-precorrin-7W. Methylation of C-15 would probably be followed by a spontaneous decarboxylation of C-12 (By similarity).

PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis; cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route): step 8/10.

SIMILARITY: Belongs to the methyltransferase superfamily. Archaeal-type CbiT family.

Pfam	PF08241; Methyltransf_11; 1;
TIGRFAMs	TIGR02469; CbiT; 1;

Cobalamin biosynthesis, Methyltransferase, S-adenosyl-L-methionine, Transferase.

GO:0008168; Molecular function: methyltransferase activity.
GO:0046140; Biological process: corrin biosynthetic process.
GO:0015420; Molecular function: cobalamin-transporting ATPase activity.

From: CBIT_METTH (O26249)
Key		From		To		Description		Condition		FTGroup
REGION		41		45		S-adenosyl-L-methionine binding (By similarity)		G-x-[GC]-[TS]-G
BINDING		17		17		S-adenosyl-L-methionine (By similarity)		T
BINDING		62		62		S-adenosyl-L-methionine (By similarity)		[DE]
BINDING		91		91		S-adenosyl-L-methionine; via amide nitrogen (By similarity)		[AVG]

Size range:	163-202 amino acids
Related UniRules:	None
Template:	O26249 (CBIT_METTH)
Scope:	Archaea
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None