HAMAP rule MF_00836
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_00836 |
| Accession | MF_00836 |
| Dates | 7-JUL-2011 (Created)
1-JUN-2023 (Last updated, Version 13) |
| Name | PhnN |
| Scope(s) |
Bacteria |
| Template(s) | P16690 (PHNN_ECOLI); [ Recover all ] |
| Triggered by |
HAMAP; MF_00836 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | PHNN |
| Protein name | RecName: Full=Ribose 1,5-bisphosphate phosphokinase PhnN; EC=2.7.4.23; AltName: Full=Ribose 1,5-bisphosphokinase; |
| Gene name | Name=phnN; |
Comments
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| FUNCTION | Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP). |
| CATALYTIC ACTIVITY | Reaction=alpha-D-ribose 1,5-bisphosphate + ATP = 5-phospho-alpha-D- ribose 1-diphosphate + ADP; Xref=Rhea:RHEA:20109, ChEBI:CHEBI:30616, ChEBI:CHEBI:58017, ChEBI:CHEBI:68688, ChEBI:CHEBI:456216; EC=2.7.4.23; |
| PATHWAY | Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route II): step 3/3. |
| SIMILARITY | Belongs to the ribose 1,5-bisphosphokinase family. |
Keywords
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Gene Ontology
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| GO:0033863; Molecular function:ribose 1,5-bisphosphate phosphokinase activity |
| GO:0006015; Biological process:5-phosphoribose 1-diphosphate biosynthetic process |
| GO:0019634; Biological process:organic phosphonate metabolic process |
Cross-references
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| PROSITE | PS50052; GUANYLATE_KINASE_2; 1; |
| Pfam | PF00625; Guanylate_kin; 1; |
| NCBIfam | TIGR02322; Phosphon_PhnN; 1; |
Features
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| From: PHNN_ECOLI (P16690) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 10 | 17 | /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616" |
G-P-S-G-[ASVG]-G-K-D | ||||||||
Additional information
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| Size range | 168-236 amino acids |
| Related rules |
None |
| Fusion | Nter: <Unknown> Cter: MF_00703 (TypH) |