HAMAP rule MF_00948

General rule information [?]

Accession	MF_00948
Dates	7-MAR-2013 (Created) 1-JUN-2023 (Last updated, Version 7)
Name	NusG
Scope(s)	Bacteria
Template(s)	P0AFG0 (NUSG_ECOLI); O67757 (NUSG_AQUAE); P29397 (NUSG_THEMA); Q06795 (NUSG_BACSU); [ Recover all ]
Triggered by	HAMAP; MF_00948 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	NUSG
Protein name	RecName: Full=Transcription termination/antitermination protein NusG;
Gene name	Name=nusG;

Comments [?]

case <OC:Enterobacterales>
FUNCTION	Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination.
SUBUNIT	Monomer. Interacts with the transcription termination factor Rho and with RNA polymerase.
else
FUNCTION	Participates in transcription elongation, termination and antitermination.
end case
SIMILARITY	Belongs to the NusG family.

Keywords [?]

Gene Ontology [?]

GO:0006354; Biological process:DNA-templated transcription elongation

GO:0006353; Biological process:DNA-templated transcription termination

GO:0031564; Biological process:transcription antitermination

Cross-references [?]

Features [?]

Additional information [?]