HAMAP rule MF_00957
General rule information
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| Accession | MF_00957 |
| Dates | 22-APR-2013 (Created)
27-JUL-2023 (Last updated, Version 8) |
| Name | PolyA_pol |
| Scope(s) |
Bacteria |
| Template(s) | P0ABF1 (PCNB_ECOLI); [ Recover all ] |
| Triggered by |
HAMAP; MF_00957 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | PCNB |
| Protein name | RecName: Full=Poly(A) polymerase I; Short=PAP I; EC=2.7.7.19; |
| Gene name | Name=pcnB; |
Comments
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| FUNCTION | Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. |
| CATALYTIC ACTIVITY | Reaction=ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide; Xref=Rhea:RHEA:11332, Rhea:RHEA-COMP:14527, Rhea:RHEA-COMP:17347, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:140395, ChEBI:CHEBI:173115; EC=2.7.7.19; |
| SIMILARITY | Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. |
Keywords
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Gene Ontology
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| GO:0005524; Molecular function:ATP binding |
| GO:1990817; Molecular function:poly(A) RNA polymerase activity |
| GO:0003723; Molecular function:RNA binding |
Cross-references
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Features
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| From: PCNB_ECOLI (P0ABF1) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| ACT_SITE | 80 | 80 | D | |||||||||
| ACT_SITE | 82 | 82 | D | |||||||||
| ACT_SITE | 162 | 162 | D | |||||||||
Additional information
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| Size range | 390-600 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |