HAMAP rule MF_00980
General rule information
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| Accession | MF_00980 |
| Dates | 12-DEC-2013 (Created)
29-SEP-2022 (Last updated, Version 7) |
| Name | RcsD |
| Scope(s) |
Bacteria Enterobacterales |
| Template(s) | P39838 (RCSD_ECOLI); [ Recover all ] |
| Triggered by |
HAMAP; MF_00980 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | RCSD |
| Protein name | RecName: Full=Phosphotransferase RcsD; EC=2.7.2.-; AltName: Full=Phosphotransfer intermediate RcsD; |
| Gene name | Name=rcsD; |
Comments
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| FUNCTION | Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB. |
| SUBUNIT | Interacts with RcsC and RcsB. |
| SUBCELLULAR LOCATION | Cell inner membrane; Multi-pass membrane protein. |
| PTM | Phosphorylated by RcsC. |
| SIMILARITY | Belongs to the RcsD family. |
Keywords
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| ATP-binding |
| Cell inner membrane |
| Cell membrane |
| Kinase |
| Membrane |
| Nucleotide-binding |
| Phosphoprotein |
| Transferase |
| Transmembrane |
| Transmembrane helix |
| Two-component regulatory system |
Gene Ontology
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| GO:0005524; Molecular function:ATP binding |
| GO:0016774; Molecular function:phosphotransferase activity, carboxyl group as acceptor |
| GO:0000160; Biological process:phosphorelay signal transduction system |
| GO:0005886; Cellular component:plasma membrane |
Cross-references
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| PROSITE | PS50109; HIS_KIN; 1; |
| PROSITE | PS50894; HPT; 1; |
| Pfam | PF02518; HATPase_c; 1; |
| Pfam | PF01627; Hpt; 1; |
| Pfam | PF00512; HisKA; 1; |
| PRINTS | PR00344; BCTRLSENSOR; 1; |
| General | Transmembrane; -; 2; |
Features
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| From: RCSD_ECOLI (P39838) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| MOD_RES | 842 | 842 | /note="Phosphohistidine" | H | ||||||||
Additional information
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| Size range | 850-950 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |