HAMAP

Accession	MF_01000
Dates	12-FEB-2002 (Created) 14-MAY-2010 (Last updated, Version 24)

Data class

Protein

Predictors

HAMAP; MF_01000; [distribution of match scores in UniProtKB];[seed alignment for MF_01000]

Names

BtuF

Identifier

BTUF

Protein name

RecName: Full=Vitamin B12-binding protein; Flags: Precursor;

Gene name

btuF

FUNCTION: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity).

SUBUNIT: The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF) (By similarity).

SUBCELLULAR LOCATION: Periplasm (By similarity).

SIMILARITY: Belongs to the BtuF family.

Pfam	PF01497; Peripla_BP_2; 1;
PROSITE	PS50983; FE_B12_PBP; 1; trigger=PRU00344;
General	Signal; -; 1; trigger=Yes;

Disulfide bond.

Periplasm, Signal, Transport.

GO:0015889; Biological process: cobalamin transport.
GO:0042597; Cellular component: periplasmic space.

From: BTUF_ECOLI (P37028)
Key		From		To		Description		Condition		FTGroup
REGION (Optional)		242		246		Cobalamin-binding (By similarity)		D-W-F-E-R
BINDING (Optional)		50		50		Cobalamin (By similarity)		Y
SITE		72		72		Important for BtuC binding (By similarity)		E
SITE		202		202		Important for BtuC binding (By similarity)		E
DISULFID		183		259		By similarity		C-x*-C

Size range:	266-280 amino acids
Related UniRules:	None
Template:	P37028 (BTUF_ECOLI)
Scope:	Bacteria; Enterobacteriaceae Bacteria; Vibrionaceae
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None