HAMAP

Accession	MF_01002
Dates	7-FEB-2002 (Created) 2-DEC-2011 (Last updated, Version 23)

Data class

Protein

Predictors

HAMAP; MF_01002; [distribution of match scores in UniProtKB];[seed alignment for MF_01002]

Names

WecF_RffT

Identifier

WECF

Protein name

RecName: Full=4-alpha-L-fucosyltransferase; EC=2.4.1.-; AltName: Full=TDP-Fuc4NAc:lipid II Fuc4NAc transferase; Short=Fuc4NAc transferase;

Gene name

wecF, rffT

FUNCTION: Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis (By similarity).

CATALYTIC ACTIVITY: TDP-Fuc4NAc + Und-PP-GlcNAc-ManNAcA = TDP + Und-PP-GlcNAc-ManNAcA-Fuc4NAc.

PATHWAY: Bacterial outer membrane biogenesis; enterobacterial common antigen biosynthesis.

SUBCELLULAR LOCATION: Cell inner membrane; Peripheral membrane protein (Potential).

SIMILARITY: Belongs to the glycosyltransferase 56 family.

Pfam	PF07429; Fuc4NAc_transf; 1;

Transferase, Glycosyltransferase, Membrane, Cell membrane, Cell inner membrane.

GO:0016758; Molecular function: transferase activity, transferring hexosyl groups.
GO:0009246; Biological process: enterobacterial common antigen biosynthetic process.
GO:0005886; Cellular component: plasma membrane.

Size range:	359-361 amino acids
Related UniRules:	None
Template:	P56258 (WECF_ECOLI)
Scope:	Bacteria; Enterobacteriaceae
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None