 |
|
| HAMAP annotation rule MF_01006 |
| Accession | MF_01006 |
| Dates | 1-MAR-2002 (Created) 2-OCT-2012 (Last updated, Version 40) |
| Name | Undec_diphosphatase |
| Scope | Bacteria Archaea |
| Triggered by |
| Identifier |
|
case <OC:Bacteria>
| Protein name |
|
||||||||||||||||
end case
case <OC:Archaea>
| Protein name |
|
||||||||||||
end case
| Gene name |
|
case <OC:Bacteria>
| FUNCTION | Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity). |
end case
case <OC:Archaea>
| FUNCTION | Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) (By similarity). |
end case
| CATALYTIC ACTIVITY | Ditrans,octacis-undecaprenyl diphosphate + H(2)O = ditrans,octacis-undecaprenyl phosphate + phosphate. |
case not defined <Property:Membrane> or <Property:Membrane=1>
| SUBCELLULAR LOCATION | Cell membrane; Multi-pass membrane protein (By similarity). |
else case <Property:Membrane=2>
| SUBCELLULAR LOCATION | Cell inner membrane; Multi-pass membrane protein (By similarity). |
end case
case <OC:Bacteria>
| MISCELLANEOUS | Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available. |
end case
| SIMILARITY | Belongs to the UppP family. |
case <OC:Bacteria>
end case
case defined <Property:Membrane> and <Property:Membrane=2>
end case
case <OC:Bacteria>
end case
GO:0050380; Molecular function: undecaprenyl-diphosphatase activity.
case <OC:Bacteria>
GO:0046677; Biological process: response to antibiotic.
end case
GO:0005886; Cellular component: plasma membrane.
| General | Transmembrane; -; 5-9; trigger=yes; |
| Size range: | 237-343 amino acids |
| Related Rules: | None |
| Templates: | P60932 (UPPP_ECOLI); P60934 (UPPP_STRPN): [Recover all] |
| Fusion: | None |
| Comments: | UPPP2 from RHILO is shorter but can not easily be extended. |