HAMAP

Accession	MF_01007
Dates	5-MAR-2002 (Created) 11-OCT-2011 (Last updated, Version 23)

Data class

Protein

Predictors

HAMAP; MF_01007; [distribution of match scores in UniProtKB];[seed alignment for MF_01007]

Names

16SrRNA_methyltr_H

Identifier

RSMH

Protein name

RecName: Full=Ribosomal RNA small subunit methyltransferase H; EC=2.1.1.199; AltName: Full=16S rRNA m(4)C1402 methyltransferase; AltName: Full=rRNA (cytosine-N(4)-)-methyltransferase RsmH;

Gene name

rsmH

FUNCTION: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity).

CATALYTIC ACTIVITY: S-adenosyl-L-methionine + cytosine(1402) in 16S rRNA = S-adenosyl-L-homocysteine + N(4)-methylcytosine(1402) in 16S rRNA.

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the methyltransferase superfamily. RsmH family.

Pfam	PF01795; Methyltransf_5; 1;
PIRSF	PIRSF004486; MraW; 1;
TIGRFAMs	TIGR00006; TIGR00006; 1;

Cytoplasm, Methyltransferase, rRNA processing, S-adenosyl-L-methionine, Transferase.

GO:0071424; Molecular function: rRNA (cytosine-N4-)-methyltransferase activity.
GO:0070475; Biological process: rRNA base methylation.
GO:0005737; Cellular component: cytoplasm.

From: RSMH_THEMA (Q9WZX6)
Key		From		To		Description		Condition		FTGroup
REGION		36		38		S-adenosyl-L-methionine binding (By similarity)		[GASC]-[GSVA]-[HY]
BINDING		55		55		S-adenosyl-L-methionine (By similarity)		[DE]
BINDING (Optional)		82		82		S-adenosyl-L-methionine; via amide nitrogen (By similarity)		[FYHILA]
BINDING		103		103		S-adenosyl-L-methionine (By similarity)		D
BINDING (Optional)		110		110		S-adenosyl-L-methionine (By similarity)		[QH]

Size range:	283-391 amino acids
Related UniRules:	None
Template:	P60390 (RSMH_ECOLI); Q9WZX6 (RSMH_THEMA); Q5SJD8 (RSMH_THET8): [Recover all]
Scope:	Bacteria
Fusion:	Nter: None; Cter: None
Duplicate:	in ACHLI, ALKMQ, CLOPH, EUBR3
Plasmid encoded:	None