HAMAP rule MF_01007
General rule information
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| Accession | MF_01007 |
| Dates | 5-MAR-2002 (Created)
1-JUN-2023 (Last updated, Version 32) |
| Name | 16SrRNA_methyltr_H |
| Scope(s) |
Bacteria |
| Template(s) | P60390 (RSMH_ECOLI); Q9WZX6 (RSMH_THEMA); Q5SJD8 (RSMH_THET8); [ Recover all ] |
| Triggered by |
HAMAP; MF_01007 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | RSMH |
| Protein name | RecName: Full=Ribosomal RNA small subunit methyltransferase H; EC=2.1.1.199; AltName: Full=16S rRNA m(4)C1402 methyltransferase; AltName: Full=rRNA (cytosine-N(4)-)-methyltransferase RsmH; |
| Gene name | Name=rsmH; |
Comments
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| FUNCTION | Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. |
| CATALYTIC ACTIVITY | Reaction=cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine = H(+) + N(4)-methylcytidine(1402) in 16S rRNA + S-adenosyl-L-homocysteine; Xref=Rhea:RHEA:42928, Rhea:RHEA-COMP:10286, Rhea:RHEA-COMP:10287, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, ChEBI:CHEBI:74506, ChEBI:CHEBI:82748; EC=2.1.1.199; |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the methyltransferase superfamily. RsmH family. |
Keywords
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Gene Ontology
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| GO:0071424; Molecular function:rRNA (cytosine-N4-)-methyltransferase activity |
| GO:0070475; Biological process:rRNA base methylation |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
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| Pfam | PF01795; Methyltransf_5; 1; |
| PIRSF | PIRSF004486; MraW; 1; |
| NCBIfam | TIGR00006; TIGR00006; 1; |
Features
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| From: RSMH_THEMA (Q9WZX6) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 36 | 38 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789" |
[GASC]-[GSVA]-[HY] | ||||||||
| BINDING | 55 | 55 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789" |
[DE] | ||||||||
| BINDING | 82 | 82 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789" |
[FYHILA] | ||||||||
| BINDING | 103 | 103 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789" |
D | ||||||||
| BINDING | 110 | 110 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789" |
[QH] | ||||||||
Additional information
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| Size range | 283-396 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |