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Annotation rule MF_01020
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General rule information [?]

Accession MF_01020
Dates 24-MAY-2002 (Created)
4-AUG-2016 (Last updated, Version 33)
Name HisE
Scope Bacteria
Archaea
Template P06989 (HIS2_ECOLI)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
HIS2
Protein name
RecName: Full=Phosphoribosyl-ATP pyrophosphatase;
Short=PRA-PH;
EC=3.6.1.31;
Gene name
hisE

Comments [?]

Catalytic activity 1-(5-phospho-beta-D-ribosyl)-ATP + H(2)O = 1-(5-phospho-beta-D-ribosyl)-AMP + diphosphate.
Pathway Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/9.
Subcellular location Cytoplasm.
Similarity Belongs to the PRA-PH family.

Keywords [?]


Gene Ontology [?]

GO:0004636; Molecular function: phosphoribosyl-ATP diphosphatase activity.
GO:0000105; Biological process: histidine biosynthetic process.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF01503; PRA-PH; 1;
TIGRFAMs TIGR03188; histidine_hisI; 1;

Additional information [?]

Size range 87-160 amino acids
Related rules MF_01019 (HIS2 supersedes the current rule)
Fusion None
Comments See MF_01019 for the entry relevant to the fused hisI-hisE