Home Proteomes Families Hamap-Scan Documents Downloads Links
HAMAP annotation rule: MF_01038
Send feedback new

General rule information

Accession MF_01038
Dates 19-DEC-2002 (Created)
11-OCT-2011 (Last updated, Version 29)
Data class Protein
Predictors HAMAP; MF_01038; [distribution of match scores in UniProtKB];[seed alignment for MF_01038]
Names GpmI


Propagated annotation

Identifier, protein and gene names
Identifier GPMI
Protein name
RecName: Full=2,3-bisphosphoglycerate-independent phosphoglycerate mutase;
Short=BPG-independent PGAM;
Short=Phosphoglyceromutase;
Short=iPGM;
EC=5.4.2.1;
Gene name gpmI
Comments
FUNCTION: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity).
CATALYTIC ACTIVITY: 2-phospho-D-glycerate = 3-phospho-D-glycerate.

case <FTGroup:1>
COFACTOR: Binds 2 manganese ions per subunit (By similarity).
end case

PATHWAY: Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5.

case <OC:Bacteria>
SUBUNIT: Monomer (By similarity).
end case


case <OG:Chloroplast>
SUBCELLULAR LOCATION: Plastid, chloroplast.
end case

SIMILARITY: Belongs to the BPG-independent phosphoglycerate mutase family.
Cross-references
Pfam PF06415; iPGM_N; 1;
PF01676; Metalloenzyme; 1;
TIGRFAMs TIGR01307; Pgm_bpd_ind; 1;
Keywords
Isomerase, Glycolysis.

case <FTGroup:1>
Metal-binding, Manganese.
end case


case <OC:Bacillaceae> and <FT:9>
Phosphoprotein.
end case

Gene Ontology
GO:0046537; Molecular function: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity.

case <FTGroup:1>
GO:0030145; Molecular function: manganese ion binding.
end case

GO:0006096; Biological process: glycolysis.

case <OG:Chloroplast>
GO:0009507; Cellular component: chloroplast.
end case

Features
From: GPMI_GEOSE (Q9X519)
Key     From     To       Description   Condition   FTGroup
ACT_SITE     62     62       Phosphoserine intermediate (By similarity)   S  
 
METAL     12     12       Manganese 2 (By similarity)   D   1
METAL     62     62       Manganese 2 (By similarity)   S   1
METAL     403     403       Manganese 1 (By similarity)   D   1
METAL     407     407       Manganese 1 (By similarity)   H   1
METAL     444     444       Manganese 2 (By similarity)   D   1
METAL     445     445       Manganese 2 (By similarity)   H   1
METAL     462     462       Manganese 1 (By similarity)   H   1
case <OC:Bacillaceae>
From: GPMI_BACSU (P39773)
Key     From     To       Description   Condition   FTGroup
MOD_RES     36     36       Phosphotyrosine (By similarity)   Y  
end case



Additional information

Size range: 490-552 amino acids
Related UniRules: MF_01402 (APGM)
Template: Q9X519 (GPMI_GEOSE); P39773 (GPMI_BACSU); P37689 (GPMI_ECOLI): [Recover all]
Scope: Bacteria
Archaea
Plastid
Fusion: Nter: None; Cter: None
Duplicate: in METAC
Plasmid encoded: None
Comments: Possible wrong start in METMA and in the second copy of gpmI in METAC. LEPIC and LEPIN seem to be more closely related to protozoan and plant gpmI than to bacterial orthologs; not shown in alignment.

View rule in raw text format (no links)



UniProtKB rule member sequences