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HAMAP annotation rule: MF_01039
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General rule information

Accession MF_01039
Dates 12-DEC-2002 (Created)
19-JUL-2011 (Last updated, Version 25)
Data class Protein
Predictors HAMAP; MF_01039; [distribution of match scores in UniProtKB];[seed alignment for MF_01039]
Names PGAM_GpmA


Propagated annotation

Identifier, protein and gene names
Identifier GPMA
Protein name
RecName: Full=2,3-bisphosphoglycerate-dependent phosphoglycerate mutase;
Short=BPG-dependent PGAM;
Short=PGAM;
Short=Phosphoglyceromutase;
Short=dPGM;
EC=5.4.2.1;
Gene name gpmA
Comments
FUNCTION: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity).
CATALYTIC ACTIVITY: 2-phospho-D-glycerate = 3-phospho-D-glycerate.
PATHWAY: Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5.

case <OC:Enterobacteriaceae>
SUBUNIT: Homodimer (By similarity).
end case

SIMILARITY: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Cross-references
Pfam PF00300; His_Phos_1; 1;
TIGRFAMs TIGR01258; Pgm_1; 1;
PROSITE PS00175; PG_MUTASE; 1;
Keywords

case <FT:4> or <FT:5> or <FT:6>
Acetylation.
end case

Isomerase, Glycolysis.
Gene Ontology
GO:0046538; Molecular function: 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity.
GO:0006096; Biological process: glycolysis.
Features
From: GPMA_ECOLI (P62707)
Key     From     To       Description   Condition   FTGroup
ACT_SITE     11     11       Tele-phosphohistidine intermediate (By similarity)   H  
ACT_SITE     184     184       By similarity   H  
SITE     62     62       Interaction with carboxyl group of phosphoglycerates (By similarity)   R  
case <OC:Escherichia> or <OC:Shigella>
Key     From     To       Description   Condition   FTGroup
MOD_RES     18     18       N6-acetyllysine (By similarity)   K  
MOD_RES     100     100       N6-acetyllysine (By similarity)   K  
MOD_RES     106     106       N6-acetyllysine (By similarity)   K  
end case



Additional information

Size range: 206-254 amino acids
Related UniRules: MF_01040 (GPMB)
Template: P62707 (GPMA_ECOLI)
Scope: Bacteria
Archaea
Fusion: Nter: None; Cter: None
Duplicate: in BACC1, BACTN, GLOVI, LACJO, LACPL, LACSS, NITEU, NITMU
Plasmid encoded: in RHIET

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UniProtKB rule member sequences