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HAMAP annotation rule: MF_01049
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General rule information

Accession MF_01049
Dates 13-FEB-2003 (Created)
11-OCT-2011 (Last updated, Version 28)
Data class Protein
Predictors HAMAP; MF_01049; [distribution of match scores in UniProtKB];[seed alignment for MF_01049]
Names CaiT


Propagated annotation

Identifier, protein and gene names
Identifier CAIT
Protein name
RecName: Full=L-carnitine/gamma-butyrobetaine antiporter;
Gene name caiT
Comments
FUNCTION: Catalyzes the exchange of L-carnitine for gamma-butyrobetaine and related betaines (By similarity).
PATHWAY: Amine and polyamine metabolism; carnitine metabolism.

case not defined <Property:Membrane> or <Property:Membrane=1>
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein (By similarity).

else case <Property:Membrane=2>
SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein (By similarity).
end case

SIMILARITY: Belongs to the BCCT transporter (TC 2.A.15) family. CaiT subfamily.
Cross-references
Pfam PF02028; BCCT; 1;
TIGRFAMs TIGR00842; Bcct; 1;
PROSITE PS01303; BCCT; 1;
General Transmembrane; -; 12; trigger=Yes;
Keywords
Transport, Antiport, Membrane, Transmembrane.

case defined <Property:Membrane> and <Property:Membrane=2>
Cell inner membrane.
end case

Cell membrane, Transmembrane helix.
Gene Ontology
GO:0015297; Molecular function: antiporter activity.
GO:0005886; Cellular component: plasma membrane.


Additional information

Size range: 504-505 amino acids
Related UniRules: None
Template: P31553 (CAIT_ECOLI)
Scope: Bacteria; Enterobacteriaceae
Fusion: Nter: None; Cter: None
Duplicate: None
Plasmid encoded: None

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UniProtKB rule member sequences