To improve security and privacy, we are moving our web pages and services from HTTP to HTTPS.
To give users of web services time to transition to HTTPS, we will support separate HTTP and HTTPS services until the end of 2017.
From January 2018 most HTTP traffic will be automatically redirected to HTTPS. [more...]
View this page in https
Annotation rule MF_01050
Send feedback

General rule information [?]

Accession MF_01050
Dates 12-MAR-2003 (Created)
18-OCT-2016 (Last updated, Version 18)
Name CaiB
Scope Bacteria; Enterobacterales
Templates P31572 (CAIB_ECOLI); Q8GB19 (CAIB_PROSL): [Recover all]

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
CAIB
Protein name
RecName: Full=L-carnitine CoA-transferase;
EC=2.8.3.21;
AltName: Full=Crotonobetainyl-CoA:carnitine CoA-transferase;
Gene name
caiB

Comments [?]

Function Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine. Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA.
Catalytic activity (E)-4-(trimethylammonio)but-2-enoyl-CoA + L-carnitine = (E)-4-(trimethylammonio)but-2-enoate + L-carnitinyl-CoA.
4-trimethylammoniobutanoyl-CoA + L-carnitine = 4-trimethylammoniobutanoate + L-carnitinyl-CoA.
Pathway Amine and polyamine metabolism; carnitine metabolism.
Subunit Homodimer.
Subcellular location Cytoplasm.
Similarity Belongs to the CaiB/BaiF CoA-transferase family.

Keywords [?]


Gene Ontology [?]

GO:0008410; Molecular function: CoA-transferase activity.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF02515; CoA_transf_3; 1;

Features [?]

From: CAIB_ECOLI (P31572)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     169     169       Nucleophile     D  
BINDING     97     97       Coenzyme A     K  
BINDING     104     104       Coenzyme A     R  

Additional information [?]

Size range 405-406 amino acids
Related rules None
Fusion None