Annotation rule MF_01050
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General rule information [?]

Accession MF_01050
Dates 12-MAR-2003 (Created)
24-MAR-2014 (Last updated, Version 16)
Name CaiB
Scope Bacteria; Enterobacteriaceae

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
CAIB
Protein name
RecName: Full=L-carnitine CoA-transferase;
EC=2.8.3.21;
AltName: Full=Crotonobetainyl-CoA:carnitine CoA-transferase;
Gene name
caiB

Comments [?]

Function Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine. Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA (By similarity).
Catalytic activity (E)-4-(trimethylammonio)but-2-enoyl-CoA + L-carnitine = (E)-4-(trimethylammonio)but-2-enoate + L-carnitinyl-CoA.
4-trimethylammoniobutanoyl-CoA + L-carnitine = 4-trimethylammoniobutanoate + L-carnitinyl-CoA.
Pathway Amine and polyamine metabolism; carnitine metabolism.
Subunit Homodimer (By similarity).
Subcellular location Cytoplasm (By similarity).
Similarity Belongs to the CaiB/BaiF CoA-transferase family.

Keywords [?]


Gene Ontology [?]

GO:0008410; Molecular function: CoA-transferase activity.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF02515; CoA_transf_3; 1;

Features [?]

From: CAIB_ECOLI (P31572)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     169     169       Nucleophile (By similarity)     D  
BINDING     97     97       Coenzyme A (By similarity)     K  
BINDING     104     104       Coenzyme A (By similarity)     R  

Additional information [?]

Size range 405-406 amino acids
Related rules None
Templates P31572 (CAIB_ECOLI); Q8GB19 (CAIB_PROSL): [Recover all]
Fusion None