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HAMAP rule MF_01051

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General rule information [?]

Accession MF_01051
Dates 18-MAR-2003 (Created)
18-AUG-2021 (Last updated, Version 20)
Name CaiD
Scope(s) Bacteria
Enterobacterales
Template(s) P31551 (CAID_ECOLI); Q8GB17 (CAID_PROSL); [ Recover all ]
Triggered by HAMAP; MF_01051 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier CAID
Protein name RecName: Full=Carnitinyl-CoA dehydratase;
                 EC=4.2.1.149;
AltName: Full=Crotonobetainyl-CoA hydratase;
Gene name Name=caiD;

Comments [?]

FUNCTIONCatalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA.
CATALYTIC ACTIVITY Reaction=(R)-carnitinyl-CoA = crotonobetainyl-CoA + H2O; Xref=Rhea:RHEA:28338, ChEBI:CHEBI:15377, ChEBI:CHEBI:60932, ChEBI:CHEBI:60933; EC=4.2.1.149;
PATHWAYAmine and polyamine metabolism; carnitine metabolism.
SIMILARITYBelongs to the enoyl-CoA hydratase/isomerase family.

Keywords [?]


Gene Ontology [?]

GO:0016836; Molecular function:hydro-lyase activity

Cross-references [?]

Pfam PF00378; ECH; 1;
PROSITE PS00166; ENOYL_COA_HYDRATASE; 1;

Features [?]

From: CAID_ECOLI (P31551)
Key From To Description Tag Condition FTGroup
ACT_SITE 111 111 /note="Nucleophile" E
ACT_SITE 131 131 /note="Proton acceptor" E

Additional information [?]

Size range 260-270 amino acids
Related rules None
Fusion Nter: None Cter: None



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