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|
| HAMAP annotation rule: MF_01057 |
| Accession |
MF_01057 |
| Dates |
12-JUN-2003 (Created)
18-OCT-2011 (Last updated, Version 20) |
| Protein name |
| RecName: |
Full=tRNA (guanine-N(7)-)-methyltransferase;
EC=2.1.1.33; |
| AltName: |
Full=tRNA (guanine(46)-N(7))-methyltransferase; |
| AltName: |
Full=tRNA(m7G46)-methyltransferase; |
|
FUNCTION: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity).
CATALYTIC ACTIVITY: S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46) in tRNA.
PATHWAY: tRNA modification; N(7)-methylguanine-tRNA biosynthesis.
case <OC:Enterobacteriaceae>
SUBUNIT: Monomer (By similarity).
end case
SIMILARITY: Belongs to the methyltransferase superfamily. TrmB family.
GO:0008176; Molecular function: tRNA (guanine-N7-)-methyltransferase activity.
GO:0006400; Biological process: tRNA modification.
| From: TRMB_ECOLI (P0A8I5) |
| Key |
|
From |
|
To |
|
Description |
|
Condition |
|
FTGroup |
| REGION (Optional) |
|
150 |
|
155 |
|
Interaction with RNA (Potential) |
|
[KR]-[KH]-[EN]-K-R-R |
|
|
| REGION (Optional) |
|
217 |
|
220 |
|
Substrate binding (Potential) |
|
T-x-[YF]-E |
|
|
| BINDING (Optional) |
|
69 |
|
69 |
|
S-adenosyl-L-methionine (By similarity) |
|
[DE] |
|
|
| BINDING (Optional) |
|
94 |
|
94 |
|
S-adenosyl-L-methionine (By similarity) |
|
[DE] |
|
|
| BINDING (Optional) |
|
121 |
|
121 |
|
S-adenosyl-L-methionine (By similarity) |
|
[DEN] |
|
|
| BINDING (Optional) |
|
144 |
|
144 |
|
S-adenosyl-L-methionine (By similarity) |
|
[DN] |
|
|
| BINDING (Optional) |
|
148 |
|
148 |
|
Substrate (By similarity) |
|
K |
|
|
| BINDING (Optional) |
|
180 |
|
180 |
|
Substrate (Potential) |
|
D |
|
|
| Size range: |
185-400 amino acids |
| Related UniRules: |
None |
| Template: |
P0A8I5 (TRMB_ECOLI); O34522 (TRMB_BACSU); P67506 (TRMB_STRPN); O66479 (TRMB_AQUAE): [Recover all] |
| Scope: |
Bacteria |
| Fusion: |
Nter: hemK, kdtA; Cter: None |
| Duplicate: |
None |
| Plasmid encoded: |
in SILPO |
| Comments: |
Fused to hemK in RICBR, RICCN, RICFE, RICPR and RICTY, and fused to kdtA in FUSNN; Unknown N-terminal domain in METPP; sequences not included in alignment and not taken into account in size range |
View rule in raw text format (no links)
